Preimplantation genetic testing can identify chromosomal abnormalities in embryos
Our New Braunfels fertility doctors offer the latest fertility treatments to help men and women conceive healthy babies. Preimplantation genetic testing, or PGT, performed with IVF, is one of many advanced fertility treatments that our New Braunfels fertility center offers. Our clinic partners with accredited genetics laboratories to identify which embryos from an IVF cycle are chromosomally normal and therefore substantially less likely to produce a baby with a chromosomal abnormality.
Preimplantation genetic testing identifies the number of chromosomes in an embryo
Preimplantation genetic testing is a way for embryologists to see the number of chromosomes in each IVF embryo. Healthy embryos have 46 chromosomes, which include two X chromosomes for females or one X chromosome and one Y chromosome for males. When our fertility doctors transfer embryos with a normal number of chromosomes, pregnancy rates are 60% to 70%.
In contrast, when an embryo has an abnormal number of chromosomes, it will often fail to implant in the uterus. These embryos may also miscarry, typically before eight to 10 weeks of gestation, or the babies may be born, usually with significant birth defects.
There are many risks associated with chromosomal abnormalities, but PGT can identify abnormalities to increase pregnancy and birth rates and reduce miscarriage rates. Additionally, research from TFC-Austin shows that routine PGT is effective for patients and insurance companies, because it significantly reduces the cost per live birth.
The process of preimplantation genetic testing occurs during an IVF cycle
Those couples who are interested in PGT undergo a typical IVF cycle. Prior to freezing or transferring the embryos, however, we add one more step to the procedure.
- Five to seven days after egg retrieval, one of our experienced embryologists from Ovation® Fertility will remove three to five cells from each embryo. At this point, each embryo has approximately 128 cells, so there is only a minimal risk of damaging the embryo by removing a small number of cells.
- The embryologist freezes the cell samples in liquid nitrogen and ships them to one of the leading genetics laboratories in the country for testing.
- After our San Antonio fertility center receives the results of your PGT testing, your fertility specialist will transfer one of the chromosomally normal embryos into your uterus.
If you are considering fertility treatment and have concerns about genetic abnormalities, board certified reproductive endocrinologist Dr. Susan Hudson can discuss these treatments with you in detail. Call Texas Fertility Center New Braunfels today for a consultation.